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HYALOVISC 1%-PFS Gel

HYALOVISC 1%-PFS Gel

Ingredient

  • Sodium hyaluronate 20 mg in 2 ml (1%),
  • MW two million Da, 

Indication

  • Rheumatoid arthritis, osteoarthritis,

Administration & Dosage

  • Injection area should be clean and free of any microorganism and skin diseases,

  • Intra-articular injection with disposable syringe,

Pharmaceutical Form

  • PFS gel,

Advantage

  • Clinical Trials have shown that injections into the knee reduce the symptoms of the disease for at least 6 months to 1 year,

Drug Interactions

  • Without any interactions,

Adverse Drug Reactions

  • Topical pain at the time of injection, swelling and stiffness that may last from 2-7 days,
  • This complication was probably due to local injection which is reversible and doesn’t prevent the use of HA injection,

Mechanism of Action

  • The high MW HA replace the synovial fluid and improves joint function,
  • The HA injection stimulates the body to make more hyaluronic acid,
  • Hyaluronic acid stabilizes the collagen network and protect the Articular cartilage against abrasion and prevents the stimulation of pain receptors,

Contraindications & Precautions

  • Allergic Reaction,
  • The bleeding disorders such as Hemophilia and anticoagulant users,
  • Pregnant or nursing mother,
  • Cancer patients,

Storage

  • Store in a dry place, keep away from direct sunlight and 20-25 °C.